Title: Sister Islands Vacation Packages 2026 from $1,256 | Expedia.com [Sister Islands Travel Guide](https://expedia.com/Sister-Islands.dx553248633946460050)[Hotels in Sister Islands](https://expedia.com/Sister-Islands-Hotels.d553248633946460050.Travel-Guide-Hotels)[Vacation Rentals in Sister Islands](https://expedia.com/Sister-Islands-Vacation-Rentals.d553248633946460050.Travel-Guide-VacationRentals)[Flights to Sister Islands](https://expedia.com/Cheap-Flights-To-Sister-Islands.d553248633946460050.Travel-Guide-Flights)[Car Rentals in Sister Islands](https://expedia.com/Car-Rentals-In-Sister-Islands.d553248633946460050.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6307499/8505b9ac-5e4b-4d71-9462-2667bf474e3e.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Sister Islands Vacations from $1,256 ## Book a Hotel + Flight or Car together to unlock savings Photo by Bob Bowdey ## The Latest Sister Islands vacation packages Price found within the past 48 hours. Click for updated prices. ![Le Soleil d'Or CaymanBrac](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/72668cc8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Le Soleil d'Or CaymanBrac Save 100% on your flight $1,256 per person May 7 - May 12 found 22 hours ago Roundtrip non-stop flight included Atlanta (ATL) to Little Cayman (LYB) 9.4/10 Exceptional! (13 reviews) The room and amenities were spotless. The food was excellent as well as the service. Beautiful and quiet Reviewed on Feb 16, 2026 Don't see what you're looking for? See all available trips from Columbus to Sister Islands [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-27/2026-04-03/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=LYB&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248633946460050) ### Discover the most popular places to visit in Sister Islands ![Beach on Little Cayman Island; Shutterstock ID 73358377; Purchase Order: -](https://images.trvl-media.com/place/6089655/f398a6b2-fea3-4632-92e8-985bf672050c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Little Cayman Beach Why not spend a carefree afternoon at Little Cayman Beach during your travels in Blossom Village? While you're in the area, wander around the parks. [](https://expedia.com/Little-Cayman-Beach-Cayman-Islands.d6089655.Vacation-Attraction) #### Cayman Brac Bluff Commune with nature and explore the great outdoors at Cayman Brac Bluff during your travels in East End. Stroll along the beaches or visit the monuments while you're in the area. [](https://expedia.com/Cayman-Brac-Bluff-East-End.d6234314.Vacation-Attraction) #### MV Captain Keith Tibbetts Shipwreck Explore the great outdoors at MV Captain Keith Tibbetts Shipwreck, a lovely green space in West End. Stroll along the beaches in this relaxing area, or seek out the snorkeling spots. [](https://expedia.com/MV-Captain-Keith-Tibbetts-Shipwreck-West-End.d6234468.Vacation-Attraction) ## Sister Islands Hotel Deals ![Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool ](https://images.trvl-media.com/lodging/45000000/44070000/44065300/44065259/471436e6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool Stake Bay Cayman Brac 10/10 Exceptional! (63 reviews) Amazing property! It has everything we needed. Master suites were very comfortable. Added bonus was being able to see and hear the ocean from bed. Very private location. We enjoyed hours on the beach! Hosts were very responsive! Reviewed on Feb 20, 2026 [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F13%2F2026&endDate=3%2F14%2F2026&selected=44065259&PinnedHotelID=44065259&HadPinnedHotel=true®ionId=553248633946460050) [](https://expedia.com/Hotel-Search?startDate=3%2F13%2F2026&endDate=3%2F14%2F2026&selected=44065259&PinnedHotelID=44065259&HadPinnedHotel=true®ionId=553248633946460050) ![Le Soleil d'Or CaymanBrac](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/72668cc8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Le Soleil d'Or CaymanBrac 2147 South Side Road West End Fully refundableReserve now, pay when you stay $443 nightly $489 total Mar 5 - Mar 6 Total with taxes and fees 9.4/10 Exceptional! (16 reviews) Awesome 👍 Reviewed on Feb 24, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&selected=74421869&PinnedHotelID=74421869&HadPinnedHotel=true®ionId=553248633946460050) ![Serenity On The Bay1 - One Bed Apt Close to Supermarkets, Shops and Restaurants!](https://images.trvl-media.com/lodging/89000000/88650000/88646400/88646355/c0f71325_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Serenity On The Bay1 - One Bed Apt Close to Supermarkets, Shops and Restaurants! West End. Cayman Brac Sister Islands 9.4/10 Exceptional! (22 reviews) The house was cleaning and match exactly as announced. Reviewed on Dec 6, 2025 [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F13%2F2026&endDate=3%2F14%2F2026&selected=88646355&PinnedHotelID=88646355&HadPinnedHotel=true®ionId=553248633946460050) [](https://expedia.com/Hotel-Search?startDate=3%2F13%2F2026&endDate=3%2F14%2F2026&selected=88646355&PinnedHotelID=88646355&HadPinnedHotel=true®ionId=553248633946460050) [See all 70 properties in Sister Islands](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026®ionId=553248633946460050) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Sister Islands Vacation Packages ## Sister Islands Essential Information | Language | English | | --------------- | -------------------------------- | | Closest Airport | Owen Roberts Intl. Airport (GCM) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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Savings not available on all packages.